Assay
Age
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Immunohistochemistry (section)
Postnatal
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Fshb follicle stimulating hormone beta (Synonyms: FSH, Fshbeta) | |
Results | Reference |
1 | J:30290 Andersen B, Pearse RV 2nd, Jenne K, Sornson M, Lin SC, Bartke A, Rosenfeld MG, The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol. 1995 Dec;172(2):495-503 |
1 | J:193143 Bouchoucha YX, Charnay P, Gilardi-Hebenstreit P, Ablation of Egr2-positive cells in male mouse anterior pituitary leads to atypical isolated GH deficiency. Endocrinology. 2013 Jan;154(1):270-82 |
1 | J:236889 Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ, ZBTB20 is required for anterior pituitary development and lactotrope specification. Nat Commun. 2016 Apr 15;7:11121 |
1 | J:99227 Charles MA, Suh H, Hjalt TA, Drouin J, Camper SA, Gage PJ, PITX genes are required for cell survival and Lhx3 activation. Mol Endocrinol. 2005 Jul;19(7):1893-903 |
1 | J:127370 Cogliati T, Delgado-Romero P, Norwitz ER, Guduric-Fuchs J, Kaiser UB, Wray S, Kirsch IR, Pubertal Impairment in Nhlh2 Null Mice Is Associated with Hypothalamic and Pituitary Deficiencies. Mol Endocrinol. 2007 Dec;21(12):3013-3027 |
1 | J:70561 Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG, Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28;97(5):587-98 |
1 | J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028 |
1 | J:310001 Ikeda Y, Tagami A, Komada M, Takahashi M, Expression of Kisspeptin in Gonadotrope Precursors in the Mouse Pituitary during Embryonic and Postnatal Development and in Adulthood. Neuroendocrinology. 2017;105(4):357-371 |
1 | J:300809 LaPierre MP, Godbersen S, Torres Esteban M, Schad AN, Treier M, Ghoshdastider U, Stoffel M, MicroRNA-7a2 Regulates Prolactin in Developing Lactotrophs and Prolactinoma Cells. Endocrinology. 2021 Feb 1;162(2) |
1 | J:104066 Mantamadiotis T, Kretz O, Ridder S, Bleckmann SC, Bock D, Grone HJ, Malaterre J, Dworkin S, Ramsay RG, Schutz G, Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice. Mol Endocrinol. 2006 Jan;20(1):204-11 |
1* | J:35634 Marcinkiewicz M, Day R, Seidah NG, Chretien M, Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4922-6 |
1 | J:140899 Million Passe CM, White CR, King MW, Quirk PL, Iovanna JL, Quirk CC, Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice. Biol Reprod. 2008 Oct;79(4):598-607 |
1 | J:182904 Moran TB, Goldberg LB, Serviss SL, Raetzman LT, Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation. Mol Endocrinol. 2011 Jan;25(1):117-27 |
1 | J:218295 Mortensen AH, Schade V, Lamonerie T, Camper SA, Deletion of OTX2 in neural ectoderm delays anterior pituitary development. Hum Mol Genet. 2015 Feb 15;24(4):939-53 |
1 | J:82562 Pulichino AM, Vallette-Kasic S, Tsai JP, Couture C, Gauthier Y, Drouin J, Tpit determines alternate fates during pituitary cell differentiation. Genes Dev. 2003 Mar 15;17(6):738-47 |
1 | J:79850 Raetzman LT, Ward R, Camper SA, Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia. Development. 2002 Sep;129(18):4229-39 |
1 | J:114717 Raetzman LT, Wheeler BS, Ross SA, Thomas PQ, Camper SA, Persistent expression of Notch2 delays gonadotrope differentiation. Mol Endocrinol. 2006 Nov;20(11):2898-908 |
1 | J:59141 Shibusawa N, Yamada M, Hirato J, Monden T, Satoh T, Mori M, Requirement of thyrotropin-releasing hormone for the postnatal functions of pituitary thyrotrophs: ontogeny study of congenital tertiary hypothyroidism in mice. Mol Endocrinol. 2000 Jan;14(1):137-46 |
1 | J:324529 Stallings CE, Kapali J, Evans BW, McGee SR, Ellsworth BS, FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth. Endocrinology. 2022 Feb 1;163(2) |
1 | J:108374 Vesper AH, Raetzman LT, Camper SA, Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology. 2006 Apr;147(4):1654-63 |
1 | J:108961 Ward RD, Stone BM, Raetzman LT, Camper SA, Cell proliferation and vascularization in mouse models of pituitary hormone deficiency. Mol Endocrinol. 2006 Jun;20(6):1378-90 |
1 | J:164366 Wen S, Ai W, Alim Z, Boehm U, Embryonic gonadotropin-releasing hormone signaling is necessary for maturation of the male reproductive axis. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16372-7 |
1* | J:13323 Wilson DB, Wyatt DP, Immunocytochemistry of ambiguous cells in adult and embryonic dwarf (dw) mouse pituitaries. Anat Rec. 1993 Aug;236(4):671-8 |
1 | J:328469 Zhang J, Zhou Y, Guo J, Li L, Liu H, Lu C, Jiang Y, Cui S, MicroRNA-7a2 is Required for the Development of Pituitary Stem Cells. Stem Cells Dev. 2022 Jul;31(13-14):357-368 |
1 | J:287133 Zhu X, Tollkuhn J, Taylor H, Rosenfeld MG, Notch-Dependent Pituitary SOX2(+) Stem Cells Exhibit a Timed Functional Extinction in Regulation of the Postnatal Gland. Stem Cell Reports. 2015 Dec 8;5(6):1196-1209 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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